• Nutrition
Ensure® Avancé

ENSURE® ADVANCE ADVANCED NUTRITION

With a formulation unique to Abbott, Ensure® Advance is complete, balanced nutrition with 20 g of high-quality protein, a caloric density of 1.5 Cal/mL, and HMB.

WHAT IS HMB? (β-hydroxy-β-methylbutyrate)

HMB is an active metabolite of leucine that helps to support muscle protein synthesis and reduce muscle protein degradation.1

  • High-protein ONS with HMB have been associated with:2-6

  • slowed or reversed muscle loss in aging, illness, or starvation;
  • improvements in wound healing, physical function, and mortality.
molecule

WHERE IS IT FOUND?

HMB is found in small amounts in some foods but is very difficult to get from diet alone.1

  • Consider this:

  • To obtain 3 g of HMB from dietary sources, one would need to eat ~600 grams of high-leucine protein sources, such as 110 eggs!1
HMB researchers

HOW HAS IT BEEN STUDIED?

HMB supplementation has been extensively studied since 1990 to conclude that HMB supports muscle health in a variety of populations.7

  • >20 studies in healthy older adults or immobilized and recovering patients
  • 27 years of research
  • 27 reviews and position papers
  • >90 published studies to date
  • References:

  • Wilkinson DJ, et al. J Physiol. 2013;591(11):2911-2923.
  • Wu H, et al. Arch Gerontol Geriatr. 2015;61:168-175.
  • Sanz-Paris A, et al. J Nutr Health Aging. 2018;22:664-675.
  • Ekinci O, et al. Nutr Clin Pract. 2016;31:829-835.
  • Cramer JT, et al. J Am Med Dir Assoc. 2016;17:1044-1055.
  • Deutz NE, et al. Clin Nutr. 2016;35:18-26.
  • Abbott Nutrition. Data on file. 2018.
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