Ensure® Advance Advanced Nutrition

With a formulation unique to Abbott, Ensure® Advance is complete, balanced nutrition with 20 g of high-quality protein, a caloric density of 1.5 Cal/mL, and HMB.

What is HMB? (β-hydroxy-β-methylbutyrate)

HMB is an active metabolite of leucine that helps to support muscle protein synthesis and reduce muscle protein degradation.1

High-protein ONS with HMB have been associated with:2-6

  • slowed or reversed muscle loss in aging, illness, or starvation;
  • improvements in wound healing, physical function, and mortality.
Ensure® Avancé Ensure® Avancé

Where is it Found?

HMB is found in small amounts in some foods but is very difficult to get from diet alone.1

Consider this:
  • To obtain 3 g of HMB from dietary sources, one would need to eat ~600 grams of high-leucine protein sources, such as 110 eggs!1
molecule

How has it been Studied?

HMB supplementation has been extensively studied since 1990 to conclude that HMB supports muscle health in a variety of populations.7

  • >20 studies in healthy older adults or immobilized and recovering patients
  • 27 years of research
  • 27 reviews and position papers
  • >90 published studies to date
HMB researchers

References:

  • Wilkinson DJ, et al. J Physiol. 2013;591(11):2911-2923.
  • Wu H, et al. Arch Gerontol Geriatr. 2015;61:168-175.
  • Sanz-Paris A, et al. J Nutr Health Aging. 2018;22:664-675.
  • Ekinci O, et al. Nutr Clin Pract. 2016;31:829-835.
  • Cramer JT, et al. J Am Med Dir Assoc. 2016;17:1044-1055.
  • Deutz NE, et al. Clin Nutr. 2016;35:18-26.
  • Abbott Nutrition. Data on file. 2018.